Cdc14B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84572

Novus Biologicals, part of Bio-Techne
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NBP1-84572
NBP1-84572-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Cited:

Primate - Macaca mulatta (Rhesus Macaque)

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cdc14B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VENQDQQEPEPYSDDDEINGVTQGDRSRAL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (83%). Monkey reactivity reported in scientific literature (PMID: 29293958).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cdc14B Antibody

Immunohistochemistry-Paraffin: Cdc14B Antibody [NBP1-84572]

Immunohistochemistry-Paraffin: Cdc14B Antibody [NBP1-84572]

Immunohistochemistry-Paraffin: Cdc14B Antibody [NBP1-84572] - Staining of human cerebellum shows strong nuclear membranous positivity in Purkinje cells.

Applications for Cdc14B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cdc14B

Cdc14B is encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Alternate Names

CDC14 cell division cycle 14 homolog B, CDC14 cell division cycle 14 homolog B (S. cerevisiae), S. cerevisiae) homolog B

Gene Symbol

CDC14B

Additional Cdc14B Products

Product Documents for Cdc14B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cdc14B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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