Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3G7

Format

BSA Free

Concentration

1 mg/ml

View all CDC37 Antibodies »

Product Specifications

Immunogen

Recombinant human CDC37 (1-378aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CDC37 Antibody (3G7) - BSA Free

Western Blot: CDC37 Antibody (3G7)BSA Free [NBP2-59466]

Western Blot: CDC37 Antibody (3G7)BSA Free [NBP2-59466]

Western Blot: CDC37 Antibody (3G7) [NBP2-59466] - Lane 1: Jurkat cell lysates, Lane 2: A431 cell lysates, Lane 3: K562 cell lysates, Lane 4: LnCap cell lysates, Lane 5: SW480 cell lysates, Lane 6: HeLa cell lysates, Lane 7: MCF7 cell lysates, Lane 8: 293T cell lysates
Immunocytochemistry/ Immunofluorescence: CDC37 Antibody (3G7) - BSA Free [NBP2-59466]

Immunocytochemistry/ Immunofluorescence: CDC37 Antibody (3G7) - BSA Free [NBP2-59466]

Immunocytochemistry/Immunofluorescence: CDC37 Antibody (3G7) [NBP2-59466] - Analysis of CDC37 in Balb/3T3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CDC37 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Applications for CDC37 Antibody (3G7) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDC37

In S. cerevisiae, Cdc37 has been shown to be an important regulator of cell division cycle through its action on cyclin-dependent kinases (CDK's). Cdc37 has also been associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase and the sevenless receptor tyrosine kinase. Interestingly, HSP90 has also been shown to be associated with many of the same cellular targets as Cdc37. It has now been shown that Cdc37 is the same protein previously described as p50 which has been found to be associated with many of the same proteins as HSP90. Among others, Cdc37/p50 has been found complexed with Src-family kinases (Fyn, Yes, Fes, Lck & Fgr), Raf and pp60v-src. More recently, Cdc37 has been shown to be a chaperone independently and in concert with HSP90. In fact, Cdc37 is necessary for the binding of HSP90 to Cdk4.

Alternate Names

CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog, CDC37 cell division cycle 37 homolog (S. cerevisiae), CDC37A, cell division cycle 37 homolog (S. cerevisiae), Hsp90 chaperone protein kinase-targeting subunit, hsp90 co-chaperone Cdc37, p50Cdc37

Gene Symbol

CDC37

Additional CDC37 Products

Product Documents for CDC37 Antibody (3G7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CDC37 Antibody (3G7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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