CDC42EP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30159

Novus Biologicals, part of Bio-Techne
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NBP3-30159
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CDC42EP1 Antibodies »

Product Specifications

Immunogen

between 150 and 200

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDC42EP1 Antibody

CDC42EP1 Antibody

Immunoprecipitation:CDC42EP1 AntibodyNBP3-30159] -

Immunoprecipitation:CDC42EP1 AntibodyNBP3-30159] -Detection of human BORG5 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BORG5 antibody NBP3-30159 used for IP at 10 µg/mg lysate. BORG5 was also immunoprecipitated by rabbit anti-BORG5., which recognizes a downstream epitope. For blotting immunoprecipitated BORG5, NBP3-30159 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.

Applications for CDC42EP1 Antibody

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CDC42EP1

CDC42EP1, also known as CDC42 Effector Protein 1, consists of a 40.2 kDa and 39.7 kDa isoform, and is involved in regulatory processes within the cell as a member of the Rho GTPase family. Most commonly found in bone marrow, the CDC42EP1 proteins been shown to help facilitate actin cytoskeleton restructuring and cell shape regulation. The protein is being studied for its involvement in osteonecrosis. The protein has been linked to the RhoA and Rho GTPases pathways where it interacts with MAPKAP1, RPTOR, RHOQ, CDC42, RBPMS, KRTAP4-12, PLSCR1.

Alternate Names

Binder of Rho GTPases 5, Borg5, BORG5cdc42 effector protein 1, CDC42 effector protein (Rho GTPase binding) 1, CEP155 kDa bone marrow stromal/endothelial cell protein, MSE55MGC15316, serum constituent protein, Serum protein MSE55

Gene Symbol

CDC42EP1

Additional CDC42EP1 Products

Product Documents for CDC42EP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CDC42EP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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