CDC42EP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88383

Novus Biologicals, part of Bio-Techne
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NBP1-88383
NBP1-88383-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CDC42EP2 Antibodies »

Product Summary for CDC42EP2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSLLSLHVDLGPSILDDVLQIMDQDLDSMQI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDC42EP2 Antibody

Western Blot: CDC42EP2 Antibody [NBP1-88383]

Western Blot: CDC42EP2 Antibody [NBP1-88383]

Western Blot: CDC42EP2 Antibody [NBP1-88383] - Analysis in control (vector only transfected HEK293T lysate) and CDC42EP2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: CDC42EP2 Antibody [NBP1-88383]

Immunocytochemistry/ Immunofluorescence: CDC42EP2 Antibody [NBP1-88383]

Immunocytochemistry/Immunofluorescence: CDC42EP2 Antibody [NBP1-88383] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & microtubules.
Immunohistochemistry-Paraffin: CDC42EP2 Antibody [NBP1-88383]

Immunohistochemistry-Paraffin: CDC42EP2 Antibody [NBP1-88383]

Immunohistochemistry-Paraffin: CDC42EP2 Antibody [NBP1-88383] - Staining of human stomach shows string cytoplasmic and membrane positivity in glandular cells.

Applications for CDC42EP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDC42EP2

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]

Alternate Names

BORG1CEP2Binder of Rho GTPases 1, CDC42 effector protein (Rho GTPase binding) 2, cdc42 effector protein 2, CRIB-containing BOGR1 protein

Gene Symbol

CDC42EP2

Additional CDC42EP2 Products

Product Documents for CDC42EP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CDC42EP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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