CDC42EP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15833

Novus Biologicals, part of Bio-Techne
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NBP2-15833
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Key Product Details

Species Reactivity

Validated:

Mouse

Predicted:

Human (100%), Rhesus Macaque (99%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CDC42EP2 Antibodies »

Product Summary for CDC42EP2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.

Reactivity Notes

Rat (89%), Bovine (88%).

Localization

Endomembrane system; Cytoplasm; cytoskeleton

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CDC42EP2 Antibody

Western Blot: CDC42EP2 Antibody [NBP2-15833]

Western Blot: CDC42EP2 Antibody [NBP2-15833]

Western Blot: CDC42EP2 Antibody [NBP2-15833] - Sample (50 ug of whole cell lysate) A: Mouse Heart, 12% SDS PAGE gel, diluted at 1:1000.

Applications for CDC42EP2 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CDC42EP2

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]

Alternate Names

BORG1CEP2Binder of Rho GTPases 1, CDC42 effector protein (Rho GTPase binding) 2, cdc42 effector protein 2, CRIB-containing BOGR1 protein

Gene Symbol

CDC42EP2

UniProt

O14613 (Human)

Additional CDC42EP2 Products

Product Documents for CDC42EP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CDC42EP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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