Cdc6 [p Ser54] Antibody (SR2085)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21570

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21570-100ul
NBP3-21570-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2085

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cdc6 Antibodies »

Product Summary for Cdc6 [p Ser54] Antibody (SR2085)

Immunogen

A synthesized peptide derived from human phospho-Cdc6 [Ser54] (Uniprot #: Q99741)

Modification

p Ser 54

Specificity

Detects endogenous levels of total phospho-Cdc6 [Ser54]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cdc6 [p Ser54] Antibody (SR2085)

Western Blot: Cdc6 [p Ser 54] Antibody (SR2085) [NBP3-21570] -

Western Blot: Cdc6 [p Ser 54] Antibody (SR2085) [NBP3-21570] - Western blot analysis using NBP3-21570 in (1) Raji cell lysate; (2) Raji + FBS cell lysate.

Applications for Cdc6 [p Ser54] Antibody (SR2085)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cdc6

Cdc6 is encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Alternate Names

CDC18LHsCDC18, Cdc18-related protein, CDC6 (cell division cycle 6, S. cerevisiae) homolog, CDC6 cell division cycle 6 homolog, CDC6 cell division cycle 6 homolog (S. cerevisiae), CDC6-related protein, cell division control protein 6 homolog, cell division cycle 6 homolog (S. cerevisiae), cell division cycle 6 protein, HsCdc18, HsCDC6, p62(cdc6)

Gene Symbol

CDC6

Additional Cdc6 Products

Product Documents for Cdc6 [p Ser54] Antibody (SR2085)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cdc6 [p Ser54] Antibody (SR2085)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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