CDC7 Antibody (SR2732)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27710

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27710-100ul
NBP3-27710-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2732

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CDC7 Antibodies »

Product Summary for CDC7 Antibody (SR2732)

Immunogen

A synthesized peptide derived from human CDC7 (Uniprot #: O00311)

Specificity

Detects endogenous levels of total CDC7

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CDC7 Antibody (SR2732)

Western Blot: CDC7 Antibody (SR2732) [NBP3-27710] -

Western Blot: CDC7 Antibody (SR2732) [NBP3-27710] - Western blot analysis of extracts from HeLa cells

Applications for CDC7 Antibody (SR2732)

Application
Recommended Usage

Flow Cytometry

1:100

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDC7

DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.

Long Name

Cell division cycle 7-related protein kinase

Alternate Names

CDC7L1, HsCdc7, huCdc7

Gene Symbol

CDC7

Additional CDC7 Products

Product Documents for CDC7 Antibody (SR2732)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CDC7 Antibody (SR2732)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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