CDK4 Antibody (CDK4/7987R) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21078V

Submit a review

Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-20642

Alexa Fluor 350

NBP3-21078AF350

Alexa Fluor 405

NBP3-21078AF405

Alexa Fluor 488

NBP3-21078AF488

Alexa Fluor 532

NBP3-21078AF532

Alexa Fluor 594

NBP3-21078AF594

Alexa Fluor 647

NBP3-21078AF647

Alexa Fluor 700

NBP3-21078AF700

Alexa Fluor 750

NBP3-21078AF750

Allophycocyanin

NBP3-21078APC

Biotin

NBP3-21078B

CoraFluor 1

NBP3-21078CL1

DyLight 350

NBP3-21078UV

DyLight 488

NBP3-21078G

DyLight 550

NBP3-21078R

DyLight 594

NBP3-21078DL594

DyLight 650

NBP3-21078C

DyLight 680

NBP3-21078FR

DyLight 755

NBP3-21078IR

FITC

NBP3-21078F

HRP

NBP3-21078H

Janelia Fluor 525

NBP3-21078JF525

Janelia Fluor 549

NBP3-21078JF549

Janelia Fluor 585

NBP3-21078JF585

Janelia Fluor 635

NBP3-21078JF635

Janelia Fluor 646

NBP3-21078JF646

Janelia Fluor 669

NBP3-21078JF669

PE

NBP3-21078PE

PerCP

NBP3-21078PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-21078

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # CDK4/7987R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CDK4 Antibodies »

Product Summary for CDK4 Antibody (CDK4/7987R) [DyLight 405]

Immunogen

Recombinant fragment corresponding to N-terminal of human CDK4 protein

Localization

Nucleus. Cytoplasm.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for CDK4 Antibody (CDK4/7987R) [DyLight 405]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CDK4

Cdk4 is encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

Long Name

Cyclin-dependent Kinase 4

Alternate Names

CMM3, PSK-J3

Gene Symbol

CDK4

Additional CDK4 Products

Product Documents for CDK4 Antibody (CDK4/7987R) [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for CDK4 Antibody (CDK4/7987R) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews