CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52673

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-52673-0.025mg
NBP2-52673-0.2mg
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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # Arcitumomab

Format

Azide and BSA Free

Concentration

1 mg/ml

View all CEACAM-5/CD66e Antibodies »

Product Specifications

Immunogen

Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion normally produced in gastrointestinal tissue during fetal development, but only at very low levels in adults.

Specificity

Recognises human carcinoembryonic antigen.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Scientific Data Images for CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free [NBP2-52673]

Immunocytochemistry/ Immunofluorescence: CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free [NBP2-52673]

Immunocytochemistry/Immunofluorescence: CEA Antibody (Arcitumomab) [NBP2-52673] - Formaldehyde-fixed rat pancreas slices were stained at 5 ug/ml and detected with a FITC-conjugated secondary antibody.
Immunohistochemistry: CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free [NBP2-52673]

Immunohistochemistry: CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free [NBP2-52673]

Immunohistochemistry: CEA Antibody (Arcitumomab) [NBP2-52673] - Formalin fixed human endometrial cancer slices were were stained with at 5 ug/ml.

Applications for CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10 - 1:500
Application Notes
This antibody is Cytof ready. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques. This antibody binds to carcinoembryonic antigen and was used in the diagnosis of mammary carcinomas.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: CEACAM-5/CD66e

The CD66e (CEA; 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 5

Alternate Names

CD66e, CEA, CEACAM5, biosimilar antibody, biosimilars

Gene Symbol

CEACAM5

Additional CEACAM-5/CD66e Products

Product Documents for CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CEACAM5/CD66e Antibody (Arcitumomab) - Chimeric - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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