Cerebellin-1/Precerebellin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77239

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Cerebellin-1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from the middle of human precerebellin. The immunogen is located within amino acids 50 - 100 of Precerebellin. Amino Acid Squence: IRSTNHEPSEMSNRT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cerebellin-1/Precerebellin Antibody - BSA Free

Western Blot: Cerebellin-1/Precerebellin AntibodyBSA Free [NBP1-77239]

Western Blot: Cerebellin-1/Precerebellin AntibodyBSA Free [NBP1-77239]

Western Blot: Cerebellin-1/Precerebellin Antibody [NBP1-77239] - Mouse cerebellum lysate with precerebellin antibody at (A) 2 and (B) 4 ug/ml.
Immunohistochemistry-Paraffin: Cerebellin-1/Precerebellin Antibody - BSA Free [NBP1-77239]

Immunohistochemistry-Paraffin: Cerebellin-1/Precerebellin Antibody - BSA Free [NBP1-77239]

Immunohistochemistry-Paraffin: Cerebellin-1/Precerebellin Antibody [NBP1-77239] - Rat brain tissue using precerebellin antibody at 2 ug/ml.
Cerebellin-1/Precerebellin Antibody - BSA Free

Western Blot: Cerebellin-1/Precerebellin Antibody - BSA Free [NBP1-77239] -

Western Blot: Cerebellin-1/Precerebellin Antibody - BSA Free [NBP1-77239] - Western blot analysis of Cerebellin-1/Precerebellin in mouse cerebellum lysate with Cerebellin-1/Precerebellin antibody at (A) 2 and (B) 4 u/mL.
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Applications for Cerebellin-1/Precerebellin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

2-4 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID:34111112)

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cerebellin-1

Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated.

Alternate Names

CBLN1, Cerebellin1, CLN1, Precerebellin

Gene Symbol

CBLN1

UniProt

P23435

Additional Cerebellin-1 Products

Product Documents for Cerebellin-1/Precerebellin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cerebellin-1/Precerebellin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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