CHD5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49186

Novus Biologicals, part of Bio-Techne
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NBP2-49186
NBP2-49186-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHD5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GYMDEKDPGAQKPRQPLEVQALPAALDRVESEDKHESPASKERAREERPEETEKAPPSPEQLPREEVLPEKEKILDKLELSLIHSR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHD5 Antibody

Immunohistochemistry: CHD5 Antibody [NBP2-49186]

Immunohistochemistry: CHD5 Antibody [NBP2-49186]

Immunohistochemistry: CHD5 Antibody [NBP2-49186] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Applications for CHD5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHD5

Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 (PubMed 12592387)).(supplied by OMIM)

Alternate Names

ATP-dependent helicase CHD5, CHD-5, chromodomain helicase DNA binding protein 5, chromodomain-helicase-DNA-binding protein 5, DKFZp434N231, EC 3.6.1, EC 3.6.4.12, KIAA0444

Gene Symbol

CHD5

Additional CHD5 Products

Product Documents for CHD5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHD5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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