CHMP2A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91780

Novus Biologicals, part of Bio-Techne
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NBP1-91780
NBP1-91780-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHMP2A Antibodies »

Product Summary for CHMP2A Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAM

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHMP2A Antibody

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780] - Staining of human thyroid gland shows high expression.
Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780]

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780] - Staining in human thyroid gland and pancreas tissues using anti-CHMP2A antibody. Corresponding CHMP2A RNA-seq data are presented for the same tissues.

Applications for CHMP2A Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP2A

Component of the escrt-iii complex, which is required for multivesicular bodies (mvbs) formation and sorting of endosomal cargo proteins into mvbs. the mvb pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. the escrt-iii complex is probably involved in the concentration of mvb cargo. in case of infection, the hiv-1 virus takes advantage of the escrt-iii complex for budding and exocytic cargos of viral proteins.

Alternate Names

BC-2, BC2VPS2 homolog A, CHMP2a, CHMP2hVps2-1, chromatin modifying protein 2A, Chromatin-modifying protein 2a, Putative breast adenocarcinoma marker BC-2, Vacuolar protein sorting-associated protein 2-1, vps2-1, VPS2Aputative breast adenocarcinoma marker (32kD), VPS2charged multivesicular body protein 2a

Gene Symbol

CHMP2A

Additional CHMP2A Products

Product Documents for CHMP2A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHMP2A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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