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CHN 1 Antibody (OTI2G6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46290

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI2G6

Concentration

1 mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human CHN1(NP_001813) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CHN 1 Antibody (OTI2G6)

Western Blot: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Western Blot: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Western Blot: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CHN 1.
Immunocytochemistry/ Immunofluorescence: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Immunocytochemistry/ Immunofluorescence: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Immunocytochemistry/Immunofluorescence: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY CHN 1.
Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290]

Immunohistochemistry-Paraffin: CHN 1 Antibody (OTI2G6) [NBP2-46290] - Analysis of Human prostate tissue.

Applications for CHN 1 Antibody (OTI2G6)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CHN 1

CHN 1 encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

a2-chimaerin, A-chimaerin, alpha-chimerin, ARHGAP2RhoGAP2, chimerin (chimaerin) 1, CHNDuane retraction syndrome 2, DURS2, NC, N-chimaerin, N-chimerin, Rho GTPase-activating protein 2, RHOGAP2

Gene Symbol

CHN1

Additional CHN 1 Products

Product Documents for CHN 1 Antibody (OTI2G6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CHN 1 Antibody (OTI2G6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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