Chondroitin sulfate synthase 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85626

Novus Biologicals, part of Bio-Techne
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NBP1-85626
NBP1-85626-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Chondroitin sulfate synthase 3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LVIILFSRDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVDLIFR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Chondroitin sulfate synthase 3 Antibody

Immunohistochemistry-Paraffin: Chondroitin sulfate synthase 3 Antibody [NBP1-85626]

Immunohistochemistry-Paraffin: Chondroitin sulfate synthase 3 Antibody [NBP1-85626]

Immunohistochemistry-Paraffin: Chondroitin sulfate synthase 3 Antibody [NBP1-85626] Staining of human kidney shows strong cytoplasmic positivity in renal tubules.

Applications for Chondroitin sulfate synthase 3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Chondroitin sulfate synthase 3

Chondroitin sulfate synthases (CHSYs) synthesize chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to various of core protein families and regulate many biologic processes, including extracellular matrix deposition, cell proliferation and recognition, and morphogenesis. The CHSY family includes CHSY1, CHSY2 and CHSY3. CHSY1 and CHSY3 display both glucuronyltransferase and N-acetylgalactosaminyltransferase activities, while CHSY2 is required for chondroitin polymerizing activity. CHSY2 localizes to the Golgi apparatus and is expressed ubiquitously, with highest expression observed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.

Alternate Names

Carbohydrate synthase 2, Chondroitin glucuronyltransferase 3, chondroitin sulfate synthase 3, Chondroitin synthase 2, chondroitin synthase-2, CHSY2, ChSy-2, CSS3N-acetylgalactosaminyltransferase 3, EC 2.4.1.175, EC 2.4.1.226, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan4-beta-N-acetylgalactosaminyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3

Gene Symbol

CHSY3

Additional Chondroitin sulfate synthase 3 Products

Product Documents for Chondroitin sulfate synthase 3 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Chondroitin sulfate synthase 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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