Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [PerCP]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11526PCP
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
PerCP (Excitation = 490 nm, Emission = 675 nm)
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # HCGab/52
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [PerCP]
Immunogen
Purified Chorionic Gonadotropin alpha/beta (hCG) protein
Localization
Cytoplasmic, Secreted
Specificity
This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Marker
Pregnancy & Choriocarcinoma Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [PerCP]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Chorionic Gonadotropin alpha/beta (HCG)
Alternate Names
Choriogonadotropin
Gene Symbol
CGB3
Additional Chorionic Gonadotropin alpha/beta (HCG) Products
Product Documents for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [PerCP]
Product Specific Notices for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [PerCP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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