CIN85/SH3KBP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85614

Novus Biologicals, part of Bio-Techne
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NBP1-85614
NBP1-85614-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CIN85/SH3KBP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDY

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CIN85/SH3KBP1 Antibody

Immunohistochemistry-Paraffin: CIN85/SH3KBP1 Antibody [NBP1-85614]

Immunohistochemistry-Paraffin: CIN85/SH3KBP1 Antibody [NBP1-85614]

Immunohistochemistry-Paraffin: CIN85/SH3KBP1 Antibody [NBP1-85614] - Staining in human lymph node and skeletal muscle tissues using anti-SH3KBP1 antibody. Corresponding SH3KBP1 RNA-seq data are presented for the same tissues.
Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614]

Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614]

Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614] - Analysis using Anti-SH3KBP1 antibody NBP1-85614 (A) shows similar pattern to independent antibody NBP1-85615 (B).
Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614]

Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614]

Western Blot: CIN85/SH3KBP1 Antibody [NBP1-85614] - Analysis in human cell line THP-1.
View 3 more images

Applications for CIN85/SH3KBP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CIN85/SH3KBP1

CBL (MIM 165360) constitutively interacts with SH3 domain-containing proteins and, upon tyrosine phosphorylation, with SH2 domain-containing proteins. The SH3KBP1 gene encodes an 85-kD CBL-interacting protein that enhances tumor necrosis factor (MIM 191160)-mediated apoptotic cell death (Narita et al., 2001 [PubMed 11474197]).[supplied by OMIM]

Long Name

Cbl-Interacting Protein of 85 KDa

Alternate Names

C-Cbl-Interacting Protein, CD2BP3, GIG10, HSB-1, MIG18, SH3KBP1

Gene Symbol

SH3KBP1

Additional CIN85/SH3KBP1 Products

Product Documents for CIN85/SH3KBP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CIN85/SH3KBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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