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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Intracellular Staining by Flow Cytometry

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # 474210

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human Claudin-8
Met1-Val225 (Ser151Pro)
Accession # P56748

Specificity

Detects human Claudin‑8. Stains human Claudin-8 transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Claudin-8 Antibody (474210) [Janelia Fluor® 646]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Claudin-8

Claudins, such as CLDN8, are components of epithelial cell tight junctions. Tight junctions regulate movement of solutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of the apical and basolateral plasma membrane domains (Acharya et al., 2004).[supplied by OMIM]

Alternate Names

Claudin8, CLDN8

Gene Symbol

CLDN8

Additional Claudin-8 Products

Product Documents for Claudin-8 Antibody (474210) [Janelia Fluor® 646]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Claudin-8 Antibody (474210) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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