CLK4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98352

Novus Biologicals, part of Bio-Techne
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NBP1-98352
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CLK4 Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody is Clk4 - N-terminal region. Peptide sequence DSDCHYLEARCLNERDYRDRRYIDEYRNDYCEGYVPRHYHRDVESTYRIH. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for CLK4 Antibody

Western Blot: CLK4 Antibody [NBP1-98352]

Western Blot: CLK4 Antibody [NBP1-98352]

Western Blot: CLK4 Antibody [NBP1-98352] - Antibody Dilution: 0.25ug/ml Sample Tissue: Mouse Pancreas.

Applications for CLK4 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLK4

Clk4 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Clk4 phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Clk4 phosphorylates SRSF1 and SRSF3. Clk4 is required for the regulation of alternative splicing of MAPT/TAU. Clk4 regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

Long Name

Dual specificity protein kinase CLK4

Alternate Names

CDC-like kinase 4

Gene Symbol

CLK4

UniProt

NP_031740 (Mouse)

Additional CLK4 Products

Product Documents for CLK4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CLK4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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