CLN3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00001201-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CLN3 Antibodies »

Product Specifications

Immunogen

CLN3 (NP_000077.1, 1 a.a. - 438 a.a.) full-length human protein. MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCRIRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDEHREFAMAATCISDTLGISLSGLLALPLHDFLCQLS

Specificity

CLN3 - ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease),

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for CLN3 Antibody

Western Blot: CLN3 Antibody [H00001201-D01P]

Western Blot: CLN3 Antibody [H00001201-D01P]

Western Blot: CLN3 Antibody [H00001201-D01P] - Analysis of CLN3 expression in mouse kidney.
Western Blot: CLN3 Antibody [H00001201-D01P]

Western Blot: CLN3 Antibody [H00001201-D01P]

Western Blot: CLN3 Antibody [H00001201-D01P] - Analysis of CLN3 expression in transfected 293T cell line by CLN3 polyclonal antibody.Lane 1: CLN3 transfected lysate(47.60 KDa).Lane 2: Non-transfected lysate.

Applications for CLN3 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against tissue lysate and transfected lysate for WB. It has been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CLN3

This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Alternate Names

Batten disease protein, Batten, Spielmeyer-Vogt disease, battenin, BTSMGC102840, ceroid-lipofuscinosis, neuronal 3, JNCL, Protein CLN3

Entrez Gene IDs

1201 (Human)

Gene Symbol

CLN3

UniProt

NP_000077.1 (Human)

Additional CLN3 Products

Product Documents for CLN3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CLN3 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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