CMYA5 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77117

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CMYA5 Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2. The immunogen is located within amino acids 3810 - 3860 of SPRYD2. Amino Acid Squence: TIRWRPTTPEATETYTLE

Specificity

SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CMYA5 Antibody - BSA Free

Western Blot: CMYA5 AntibodyBSA Free [NBP1-77117]

Western Blot: CMYA5 AntibodyBSA Free [NBP1-77117]

Western Blot: CMYA5 Antibody [NBP1-77117] - Analysis in mouse heart tissue lysate with antibody at 1 ug/mL.
Immunohistochemistry: CMYA5 Antibody - BSA Free [NBP1-77117]

Immunohistochemistry: CMYA5 Antibody - BSA Free [NBP1-77117]

Immunohistochemistry: CMYA5 Antibody [NBP1-77117] - SPRYD2 in mouse brain tissue with SPRYD2 antibody at 20 ug/mL.
Immunohistochemistry: CMYA5 Antibody - BSA Free [NBP1-77117]

Immunohistochemistry: CMYA5 Antibody - BSA Free [NBP1-77117]

Immunohistochemistry: CMYA5 Antibody [NBP1-77117] - SPRYD2 in mouse brain tissue with SPRYD2 antibody at 2.5 ug/mL.

Applications for CMYA5 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/mL

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CMYA5

SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.

Alternate Names

C5orf10, cardiomyopathy associated 5, cardiomyopathy-associated protein 5, DKFZp451G182, DKFZp451G223, DTNBP2, dystrobrevin-binding protein 2, genethonin-3, myospryn, SPRY domain-containing protein 2, SPRYD2, tripartite motif-containing protein 76

Gene Symbol

CMYA5

UniProt

NP_705838 (Human)

Additional CMYA5 Products

Product Documents for CMYA5 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CMYA5 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.