CNGB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75087

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Cited:

Primate - Macaca mulatta (Rhesus Macaque)

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Peptide ELISA

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CNGB3 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-ESDDKPTEHYYR, from the internal region of the protein sequence according to NP_061971.3.

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589) .

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CNGB3 Antibody

Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087]

Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087]

Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087] - Negative Control showing staining of paraffin embedded Human Retina, with no primary antibody.
Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087]

Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087]

Immunohistochemistry-Paraffin: CNGB3 Antibody [NBP2-75087] - (2ug/ml) staining of paraffin embedded Human Retina. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for CNGB3 Antibody

Application
Recommended Usage

Immunohistochemistry

2-4 ug/ml

Immunohistochemistry-Paraffin

2-4 ug/ml

Peptide ELISA

1:8000
Application Notes
Use in Immunohistochemistry-Frozen reported in scientific literature (PMID:35024589)..

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

TBS (pH 7.3), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CNGB3

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 . Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones

Alternate Names

cyclic nucleotide gated channel beta 3

Gene Symbol

CNGB3

Additional CNGB3 Products

Product Documents for CNGB3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CNGB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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