Coagulation Factor II/Thrombin Antibody (046)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90542

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90542-100ul
NBP2-90542-50ul
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 046

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Coagulation Factor II/Thrombin Antibodies »

Product Summary for Coagulation Factor II/Thrombin Antibody (046)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Coagulation Factor II/Thrombin (Accession#: NP_034298.1; Met1-Gly618).

Specificity

No cross-reactivity in ELISA with: Mouse KLK1Mouse KLK11

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for Coagulation Factor II/Thrombin Antibody (046)

Application
Recommended Usage

ELISA

1:5000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Coagulation Factor II/Thrombin

Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.

Alternate Names

F2, Thrombin

Gene Symbol

F2

Additional Coagulation Factor II/Thrombin Products

Product Documents for Coagulation Factor II/Thrombin Antibody (046)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Coagulation Factor II/Thrombin Antibody (046)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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