Coagulation Factor III/Tissue Factor Antibody (HTF-1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62199

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Functional, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # HTF-1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Coagulation Factor III/Tissue Factor Antibodies »

Product Specifications

Immunogen

Human brain tissue factor (CD142)

Specificity

The antibody MEM-25 reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Coagulation Factor III/Tissue Factor Antibody (HTF-1)

Immunohistochemistry-Paraffin: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199]

Immunohistochemistry-Paraffin: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199]

Immunohistochemistry-Paraffin: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199] - Staining of human cortex (paraffin-embedded sections) with anti-CD142 (HTF-1), 10 ug/ml.
Flow Cytometry: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199]

Flow Cytometry: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199]

Flow Cytometry: Coagulation Factor III/Tissue Factor Antibody (HTF-1) [NBP2-62199] - Surface staining of PHA activated human peripheral blood cells using anti-CD142 (HTF-1) PE.

Applications for Coagulation Factor III/Tissue Factor Antibody (HTF-1)

Application
Recommended Usage

Flow Cytometry

3-12 ug/ml

Western Blot

1-2 ug/ml.
Application Notes
Western blotting: Reducing conditions preferred.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Coagulation Factor III/Tissue Factor

Tissue Factor encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [provided by RefSeq]

Alternate Names

CD142, F3, Thromboplastin, Tissue Factor

Gene Symbol

F3

Additional Coagulation Factor III/Tissue Factor Products

Product Documents for Coagulation Factor III/Tissue Factor Antibody (HTF-1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Coagulation Factor III/Tissue Factor Antibody (HTF-1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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