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COG8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15938

Novus Biologicals, part of Bio-Techne
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NBP2-15938

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (90%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for COG8 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human COG8. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%).

Localization

Golgi apparatus membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

68 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for COG8 Antibody

Western Blot: COG8 Antibody [NBP2-15938]

Western Blot: COG8 Antibody [NBP2-15938]

Western Blot: COG8 Antibody [NBP2-15938] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: COG8 Antibody [NBP2-15938]

Immunocytochemistry/ Immunofluorescence: COG8 Antibody [NBP2-15938]

Immunocytochemistry/Immunofluorescence: COG8 Antibody [NBP2-15938] - Immunofluorescence analysis of methanol-fixed A431, using antibody at 1:500 dilution.

Applications for COG8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: COG8

This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance. [provided by RefSeq]

Alternate Names

COG complex subunit 8, component of oligomeric golgi complex 8CDG2H, conserved oligomeric Golgi complex subunit 8, dependent on RIC1, DOR1conserved oligomeric golgi complex component 8, FLJ22315

Gene Symbol

COG8

UniProt

Additional COG8 Products

Product Documents for COG8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for COG8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.