Complement C3d Antibody (C3D/2891)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07741

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C3D/2891

Concentration

0.2 mg/ml

View all Complement C3d Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 1250-1450) of human Complement C3d protein (exact sequence is proprietary) (Uniprot: P01024)

Localization

Plasma.

Marker

Acute Humoral Rejection Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08764)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for Complement C3d Antibody (C3D/2891)

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741] - Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with Complement C3d Antibody (C3D/2891) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. HRP-polymer, 30min. DAB, 5min.
Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Immunohistochemistry-Paraffin: Complement C3d Antibody (C3D/2891) [NBP3-07741] - Formalin-fixed, paraffin-embedded human rejected kidney transplant stained with Complement C3d Antibody (C3D/2891) at 2ug/ml in PBS. HIER: Tris/EDTA, pH9.0, 45min. HRP-polymer, 30min. DAB, 5min.
Protein Array: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Protein Array: Complement C3d Antibody (C3D/2891) [NBP3-07741]

Protein Array: Complement C3d Antibody (C3D/2891) [NBP3-07741] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Complement C3d Mouse Monoclonal Antibody (C3D/2891).

Applications for Complement C3d Antibody (C3D/2891)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Complement C3d

C3d is a fragment of the major complement protein C3, C3d is formed as a result of the deactivation of C3b.Factor I in the presence of cofactors cleaves C3b to form iC3b and C3f, Factor I and/or other proteasesthen cleaves iC3b to form C3c and C3dg. C3dg is then further cleaved by tryptic enzymes to C3g andC3d. The C3 fragments are then eliminated from circulation by phagocytic cells in the liver. C3d has amolecular weight of 34kDa. Normally C3d is present in trace amounts in plasma, however, in diseasestates where rapid complement consumption is occurring levels of C3d can be elevated.

Alternate Names

AHUS5, ARMD9, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, complement C3, complement component 3, complement component C3, CPAMD1acylation-stimulating protein cleavage product

Gene Symbol

C3

UniProt

P01024

Additional Complement C3d Products

Product Documents for Complement C3d Antibody (C3D/2891)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Complement C3d Antibody (C3D/2891)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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