Complement Factor I Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88267

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Complement Factor I Antibodies »

Product Summary for Complement Factor I Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVAQEETEILTADMDAERRRIKSLLPKLSC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Complement Factor I Antibody

Complement Factor I Antibody Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Complement Factor I Antibody Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Staining of human epididymis shows strong positivity in plasma in blood vessels.
Complement Factor I Antibody Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88267]

Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
View 1 more images

Applications for Complement Factor I Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Complement Factor I

Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

Alternate Names

C3b Inactivator, CFI

Gene Symbol

CFI

Additional Complement Factor I Products

Product Documents for Complement Factor I Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Complement Factor I Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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