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Connexin 31/GJB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57376

Novus Biologicals, part of Bio-Techne
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NBP2-57376
NBP2-57376-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Connexin 31/GJB3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Connexin 31/GJB3 Antibody

Immunocytochemistry/ Immunofluorescence: Connexin 31/GJB3 Antibody [NBP2-57376]

Immunocytochemistry/ Immunofluorescence: Connexin 31/GJB3 Antibody [NBP2-57376]

Immunocytochemistry/Immunofluorescence: Connexin 31/GJB3 Antibody [NBP2-57376] - Staining of human cell line A-431 shows localization to cell junctions.

Applications for Connexin 31/GJB3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Connexin 31/GJB3

GJB3 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternate Names

DFNA2, DFNA2B, EKV, GJB3

Gene Symbol

GJB3

Additional Connexin 31/GJB3 Products

Product Documents for Connexin 31/GJB3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Connexin 31/GJB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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