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COP9 signalosome complex subunit 2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93557

Novus Biologicals, part of Bio-Techne
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NB100-93557
NB100-93557SS

Key Product Details

Species Reactivity

Human, Mouse, Rat, Drosophila

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide of residues 239-250 [ECGGKMHLREGE].

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat and Drosophila

Specificity

This product shares 100% homology to mouse, rat and Drosophila melanogaster alien isoform B protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COP9 signalosome complex subunit 2 Antibody - BSA Free

Western Blot: COP9 signalosome complex subunit 2 AntibodyBSA Free [NB100-93557]

Western Blot: COP9 signalosome complex subunit 2 AntibodyBSA Free [NB100-93557]

Western Blot: COP9 signalosome complex subunit 2 Antibody [NB100-93557] - Analysis of Alien in HeLa cells using NB100-93557 at 1:500 dilution.

Applications for COP9 signalosome complex subunit 2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:100-1:2000
Application Notes
This antibody is useful for Western Blot.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COP9 signalosome complex subunit 2

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Alternate Names

ALIEN, Alien homolog, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9 signalosome complex subunit 2, CSN2JAB1-containing signalosome subunit 2, SGN2TR-interacting protein 15, Signalosome subunit 2, thyroid receptor interacting protein 15, Thyroid receptor-interacting protein 15, TRIP15TRIP-15

Entrez Gene IDs

9318 (Human); 12848 (Mouse); 261736 (Rat)

Gene Symbol

COPS2

Additional COP9 signalosome complex subunit 2 Products

Product Documents for COP9 signalosome complex subunit 2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for COP9 signalosome complex subunit 2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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