COP9 signalosome complex subunit 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31481

Novus Biologicals, part of Bio-Techne
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NBP1-31481
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Chicken (100%), Monkey (100%), Porcine (100%), Rat (100%), Xenopus (100%), Zebrafish (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all COP9 signalosome complex subunit 2 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COP9 signalosome complex subunit 2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Rhesus Monkey (100%).

Localization

Cytoplasm, Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COP9 signalosome complex subunit 2 Antibody

Western Blot: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Western Blot: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Western Blot: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 C: Hela 10% SDS PAGE TRIP15antibody, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Immunocytochemistry/ Immunofluorescence: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Immunocytochemistry/Immunofluorescence: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - Paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NBP1-31481]

Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - COP9 antibody detects COP9 protein at cytoplasm and nucleus on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain.COP9 antibody diluted at 1:500. Antigen Retrieval: Trilogy (EDTA based, pH 8.0) buffer, 15min
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Applications for COP9 signalosome complex subunit 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: COP9 signalosome complex subunit 2

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Alternate Names

ALIEN, Alien homolog, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis), COP9 signalosome complex subunit 2, CSN2JAB1-containing signalosome subunit 2, SGN2TR-interacting protein 15, Signalosome subunit 2, thyroid receptor interacting protein 15, Thyroid receptor-interacting protein 15, TRIP15TRIP-15

Gene Symbol

COPS2

Additional COP9 signalosome complex subunit 2 Products

Product Documents for COP9 signalosome complex subunit 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for COP9 signalosome complex subunit 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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