COPR5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30884

Novus Biologicals, part of Bio-Techne
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NBP2-30884
NBP2-30884-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Block/Neutralize, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all COPR5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EAGFATADHSGQERETEKAMDRLARGTQSIPNDSPARGEGTHSEEEGFAMDEEDSDGELNTWELSEGTNCPPKE

Reactivity Notes

Mouse reactivity validated from a verified customer review.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COPR5 Antibody

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884] - Staining of human skeletal muscle shows moderate nuclear positivity in myocytes.
Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884]

Immunohistochemistry-Paraffin: COPR5 Antibody [NBP2-30884] - Staining of human colon shows strong nuclear and moderate cytoplasmic positivity in glandular cells.
View 1 more images

Applications for COPR5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

Validated from a verified customer review
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 4 using NBP2-30884 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COPR5

COPR5 is a Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that COPR5 acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression.

Alternate Names

C17orf79, chromosome 17 open reading frame 79, cooperator of PRMT5, COPR5, FLJ21119, HSA272196, Protein TTP1, TTP1

Gene Symbol

COPRS

UniProt

Q9NQ92 (Human)

Additional COPR5 Products

Product Documents for COPR5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for COPR5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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