CORO1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49634

Novus Biologicals, part of Bio-Techne
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NBP2-49634
NBP2-49634-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CORO1B Antibodies »

Product Summary for CORO1B Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAAGATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CORO1B Antibody

Western Blot: CORO1B Antibody [NBP2-49634]

Western Blot: CORO1B Antibody [NBP2-49634]

Western Blot: CORO1B Antibody [NBP2-49634] - Analysis in human cell lines MCF-7 and U-251MG using anti-CORO1B antibody. Corresponding CORO1B RNA-seq data are presented for the same cell lines. Loading control: anti-PPIB.
Immunohistochemistry-Paraffin: CORO1B Antibody [NBP2-49634]

Immunohistochemistry-Paraffin: CORO1B Antibody [NBP2-49634]

Immunohistochemistry-Paraffin: CORO1B Antibody [NBP2-49634] - Staining of human Prostate shows strong cytoplasmic positivity in glandular cells.
Western Blot: CORO1B Antibody [NBP2-49634]

Western Blot: CORO1B Antibody [NBP2-49634]

Western Blot: CORO1B Antibody [NBP2-49634] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251 MG
Lane 4: Human plasma
Lane 5: Human Liver tissue
Lane 6: Human Tonsil tissue
View 8 more images

Applications for CORO1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1:100 - 1:250
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CORO1B

Coronin 2 is an F-actin binding protein that plays an important role in processes involving actin dynamics such as fibroblast migration, and phagocytosis. Coronin 2 influences actin dynamics by promoting actin depolymerization. It has been shown to interact with the Arp2/3 complex and inhibit Arp2/3-induced actin nucleation. Additionally, it can regulate motility by regulating the actin severing and disassembling activity of cofilin.

Alternate Names

coronin, actin binding protein, 1B, coronin, actin-binding protein, 1B, coronin-1B, Coronin-2, DKFZp762I166

Gene Symbol

CORO1B

Additional CORO1B Products

Product Documents for CORO1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CORO1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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