COX-1 Antibody (8L4X10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16214

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16214-100ul
NBP3-16214-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8L4X10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all COX-1 Antibodies »

Product Summary for COX-1 Antibody (8L4X10)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human COX-1 (P23219). GLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COX-1 Antibody (8L4X10)

Western Blot: COX-1 Antibody (8L4X10) [NBP3-16214]

Western Blot: COX-1 Antibody (8L4X10) [NBP3-16214]

Western Blot: COX-1 Antibody (8L4X10) [NBP3-16214] - Western blot analysis of extracts of various cell lines, using COX-1 Rabbit mAb (NBP3-16214) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Applications for COX-1 Antibody (8L4X10)

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: COX-1

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

Long Name

Cyclooxygenase 1

Alternate Names

COX1, PTGS1

Gene Symbol

PTGS1

Additional COX-1 Products

Product Documents for COX-1 Antibody (8L4X10)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for COX-1 Antibody (8L4X10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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