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COX IV Isoform 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13152

Novus Biologicals, part of Bio-Techne
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NBP3-13152

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COX IV Isoform 2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for COX IV Isoform 2 Antibody

Immunocytochemistry/ Immunofluorescence: COX IV Isoform 2 Antibody [NBP3-13152]

Immunocytochemistry/ Immunofluorescence: COX IV Isoform 2 Antibody [NBP3-13152]

Immunocytochemistry/Immunofluorescence: COX IV Isoform 2 Antibody [NBP3-13152] - COX IV Isoform 2 antibody detects COX IV Isoform 2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: COX IV Isoform 2 stained by COX IV Isoform 2 antibody (NBP3-13152) diluted at 1:1000. Blue: Hoechst 33342 staining. Scale bar= 10um.
Immunohistochemistry-Paraffin: COX IV Isoform 2 Antibody [NBP3-13152]

Immunohistochemistry-Paraffin: COX IV Isoform 2 Antibody [NBP3-13152]

Immunohistochemistry-Paraffin: COX IV Isoform 2 Antibody [NBP3-13152] - COX IV Isoform 2 antibody detects COX IV Isoform 2 protein at mitochondria by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. COX IV Isoform 2 stained by COX IV Isoform 2 antibody (NBP3-13152) diluted at 1:500. Antigen Retrieval: Tris-EDTA buffer, pH 9.0, 15 min

Applications for COX IV Isoform 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COX4-I2

COX4-1 (Cytochrome c oxidase subunit 4 isoform 1) is a 21-22 kDa member of the Cytochrome c oxidase IV family of proteins and is predominantly expressed in lung. It is a component of COX, an inner mitochondrial membrane multimeric dimer that catalyzes the transfer of electrons from Cytochrome c to dioxygen. COX4-I2 is induced following blockade of mitochondrial respiration, leading to increased production of reactive oxygen species and necrosis. The ubiquitously expressed COX4-I1 is the product of a different gene and shares only 50% aa identity with COX4-I2.

Long Name

Cytochrome c Oxidase Subunit IV Isoform 2

Alternate Names

COX4-2, COX4B, COX4L2, COXIV-2

Gene Symbol

COX4I2

Additional COX4-I2 Products

Product Documents for COX IV Isoform 2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for COX IV Isoform 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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