COX18 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59616

Novus Biologicals, part of Bio-Techne
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NBP1-59616
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all COX18 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to COX18(COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)) The peptide sequence was selected from the middle region of COX18. Peptide sequence LCSSFVGLSQNLLLRSPGFRQLCRIPSTKSDSETPYKDIFAAFNTKFISR. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for COX18 Antibody

Western Blot: COX18 Antibody [NBP1-59616]

Western Blot: COX18 Antibody [NBP1-59616]

Western Blot: COX18 Antibody [NBP1-59616] - Human Muscle lysate, concentration 0.2-1 ug/ml.

Applications for COX18 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COX18

COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c

Alternate Names

COX18 cytochrome c oxidase assembly homolog (S. cerevisiae), COX18HS, Cox18Hs1 protein, Cox18Hs2 protein, Cox18Hs3 protein, Cytochrome c oxidase assembly protein 18, FLJ38991, MGC126733, mitochondrial COX18, mitochondrial inner membrane protein COX18, OXA1L2

Gene Symbol

COX18

UniProt

Q8N8Q8 (Human)

Additional COX18 Products

Product Documents for COX18 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for COX18 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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