CRB1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41201

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CRB1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1. Amino Acid Squence: ISLKIKPYKIELYQSSQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%)

Specificity

Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

142 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CRB1 Antibody - BSA Free

Western Blot: CRB1 AntibodyBSA Free [NBP2-41201]

Western Blot: CRB1 AntibodyBSA Free [NBP2-41201]

Western Blot: CRB1 Antibody [NBP2-41201] - Analysis of CRB1 in human small intestine Tissue lysate with CRB1 antibody at 1 ug/mL.

Applications for CRB1 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1 - 2 ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRB1

CRB1, also known as Protein crumbs homolog 1, contains several isoforms that are 154 kDa, 151 kDa, 142 kDa, 104 kDa, and 95 kDa, and is involved in the development of photoreceptors in the retina. Defects and mutations in the CRB1 protein result in a variety of disorders, and more research is currently being conducted on the protein's relation to other diseases, including pigmented paravenous chorioretinal atrophy, cone-rod dystrophy, Stargardt disease, keratoconus, retinal degeneration, hyperopia, tuberous sclerosis, and blindness. The protein is linked to epithelial tight junction pathways, and interacts with INADL, MPP5, PSMD13, PRKAR1A, and DDX56.

Alternate Names

crumbs homolog 1 (Drosophila), LCA8

Gene Symbol

CRB1

Additional CRB1 Products

Product Documents for CRB1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRB1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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