CRCP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84495

Novus Biologicals, part of Bio-Techne
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NBP1-84495
NBP1-84495-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CRCP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TPCRHQSPEIVREFLTALKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAEPEAEQKKNTNSNVAMDEEDPA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRCP Antibody

Western Blot: CRCP Antibody [NBP1-84495]

Western Blot: CRCP Antibody [NBP1-84495]

Western Blot: CRCP Antibody [NBP1-84495] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 10. Lane 2: Human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: CRCP Antibody [NBP1-84495]

Immunocytochemistry/ Immunofluorescence: CRCP Antibody [NBP1-84495]

Immunocytochemistry/Immunofluorescence: CRCP Antibody [NBP1-84495] - Staining of human cell line A-431 shows localization to nuclear bodies. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: CRCP Antibody [NBP1-84495]

Immunohistochemistry-Paraffin: CRCP Antibody [NBP1-84495]

Immunohistochemistry-Paraffin: CRCP Antibody [NBP1-84495] - Staining of human testis shows cytoplasmic and nuclear positivity of cells in seminiferus ducts.

Applications for CRCP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRCP

CRCP, also known as DNA-directed RNA polymerase III subunit RPC9, is a 17 kDa 148 amino acid protein with three shorter isoforms. The primary function of CRCP is to encode a protein which plays a role in increasing intracellular cAMP levels. CRCP is currently being studied in relation to cystic fibrosis, cryptorchidism, fibrosis, pancreatic cancer and pancreatitis. CRCP has been linked to the cellular localization, acrosome reaction, vasodilation, pathogenesis and parturition pathways where it interacts with POLD3, CHRAC1, VAV2, CALCRL and POLR3H.

Alternate Names

Calcitonin gene-related peptide-receptor component protein, CGRP receptor component, CGRPRCP, CGRP-RCPRNA polymerase III subunit C9, CGRP-receptor component protein, DNA-directed RNA polymerase III subunit RPC9, hsC17, RCP9, RCPMGC111194

Entrez Gene IDs

27297 (Human)

Gene Symbol

CRCP

UniProt

O75575 (Human)

Additional CRCP Products

Product Documents for CRCP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRCP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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