CREB [p Ser133] Antibody (SR1800)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21507

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21507-100ul
NBP3-21507-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1800

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CREB Antibodies »

Product Summary for CREB [p Ser133] Antibody (SR1800)

Immunogen

A synthesized peptide derived from human phospho-Creb [Ser133] (Uniprot #: P16220)

Modification

p Ser133

Specificity

Detects endogenous levels of total phospho-Creb [Ser133]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CREB [p Ser133] Antibody (SR1800)

Immunohistochemistry: CREB [p Ser 133] Antibody (SR1800) [NBP3-21507] -

Immunohistochemistry: CREB [p Ser 133] Antibody (SR1800) [NBP3-21507] - Immunohistochemical analysis of paraffin-embedded human gastric carcinoma, using NBP3-21507.

Western Blot: CREB [p Ser 133] Antibody (SR1800) [NBP3-21507] -

Western Blot: CREB [p Ser 133] Antibody (SR1800) [NBP3-21507] - Western blot analysis using NBP3-21507 in HeLa cell lysates treated with Calyculin A.

Applications for CREB [p Ser133] Antibody (SR1800)

Application
Recommended Usage

Flow Cytometry

1:40

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:40

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CREB

CREB (cAMP responsive element binding protein 1) stimulates transcription. CREB is involved in learning and memory. This protein is known to have interactions with HIST1H3B, HIST1h3A, HIST1H3C, HIST1H3D and HIST1H3E. CREB has been studied in relation to several diseases and disorders including Rubinstein-Taybi syndrome, Alzheimer's disease, leukemia and brain disease.

Long Name

cAMP Response Element-binding Protein

Alternate Names

CREB1

Gene Symbol

CREB1

Additional CREB Products

Product Documents for CREB [p Ser133] Antibody (SR1800)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CREB [p Ser133] Antibody (SR1800)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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