CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15330

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15330-100ul
NBP3-15330-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1W4T4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CSE1L/CAS Antibodies »

Product Summary for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 872-971 of human CSE1L/CAS/Exportin-2 (P55060). LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAASVTLL

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (1W4T4) [NBP3-15330] - Western blot analysis of extracts of various cell lines, using CSE1L/CAS/Exportin-2 Rabbit mAb (NBP3-15330) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CSE1L/CAS

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Long Name

Chromosome segregation 1-like protein

Alternate Names

CAS, CSE1, XPO2

Gene Symbol

CSE1L

Additional CSE1L/CAS Products

Product Documents for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CSE1L/CAS/Exportin-2 Antibody (1W4T4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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