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CSP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00080331-B01P

Novus Biologicals, part of Bio-Techne
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H00080331-B01P

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

DNAJC5 (NP_079495.1, 1 a.a. - 198 a.a.) full-length human protein. MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for CSP Antibody

Western Blot: CSP Antibody [H00080331-B01P]

Western Blot: CSP Antibody [H00080331-B01P]

Western Blot: CSP Antibody [H00080331-B01P] - Analysis of DNAJC5 expression in rat brain.
Immunocytochemistry/ Immunofluorescence: CSP Antibody [H00080331-B01P]

Immunocytochemistry/ Immunofluorescence: CSP Antibody [H00080331-B01P]

Immunocytochemistry/Immunofluorescence: CSP Antibody [H00080331-B01P] - Analysis of purified antibody to DNAJC5 on HeLa cell. (antibody concentration 10 ug/ml)
Western Blot: CSP Antibody [H00080331-B01P]

Western Blot: CSP Antibody [H00080331-B01P]

Western Blot: CSP Antibody [H00080331-B01P] - Analysis of DNAJC5 expression in transfected 293T cell line by DNAJC5 polyclonal antibody. Lane 1: DNAJC5 transfected lysate(21.78 KDa). Lane 2: Non-transfected lysate.

Applications for CSP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is useful for Western Blot, Immunofluorescence

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSP

Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle, possibly via palmitoylation. CSP homologs are localized to the nervous system of Drosophila and to cholinergic vesicles of Torpedo. The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heatshock protein family. Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation. CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature.

Alternate Names

CSP, Cysteine string protein, cysteine string protein alpha, DKFZp434N1429, DKFZp761N1221, DnaJ (Hsp40) homolog, subfamily C, member 5, dnaJ homolog subfamily C member 5, DNAJC5A, FLJ00118, FLJ13070

Gene Symbol

DNAJC5

Additional CSP Products

Product Documents for CSP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CSP Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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