CSP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-74397

Novus Biologicals, part of Bio-Techne
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NB100-74397
NB100-74397-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all CSP Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues E(180) T T Q L T A D S H P S Y H T D G F N(198) of rat CSP.

Specificity

Cysteine String Protein alpha

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CSP Antibody

Western Blot: CSP Antibody [NB100-74397]

Western Blot: CSP Antibody [NB100-74397]

Western Blot: CSP Antibody [NB100-74397] - Analysis rat brain samples.

Applications for CSP Antibody

Application
Recommended Usage

Western Blot

1:1000
Application Notes
WB: Detects an approx. 34 kDa protein.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CSP

Cysteine string protein (CSP) is a 34 kDa rat brain protein localized to the cytoplasmic surface of the synaptic vesicle, possibly via palmitoylation. CSP homologs are localized to the nervous system of Drosophila and to cholinergic vesicles of Torpedo. The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heatshock protein family. Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation. CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature.

Alternate Names

CSP, Cysteine string protein, cysteine string protein alpha, DKFZp434N1429, DKFZp761N1221, DnaJ (Hsp40) homolog, subfamily C, member 5, dnaJ homolog subfamily C member 5, DNAJC5A, FLJ00118, FLJ13070

Entrez Gene IDs

13002 (Mouse)

Gene Symbol

DNAJC5

Additional CSP Products

Product Documents for CSP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CSP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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