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CSTF2T Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00023283-B01P

Novus Biologicals, part of Bio-Techne
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H00023283-B01P

Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CSTF2T (NP_056050.1, 1 a.a. - 616 a.a.) full-length human protein. MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS

Reactivity Notes

This product is reactive against Human,Rat.

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for CSTF2T Antibody

Western Blot: CSTF2T Antibody [H00023283-B01P]

Western Blot: CSTF2T Antibody [H00023283-B01P]

Western Blot: CSTF2T Antibody [H00023283-B01P] - Analysis of CSTF2T expression in rat brain.
Western Blot: CSTF2T Antibody [H00023283-B01P]

Western Blot: CSTF2T Antibody [H00023283-B01P]

Western Blot: CSTF2T Antibody [H00023283-B01P] - Analysis of CSTF2T expression in transfected 293T cell line by CSTF2T polyclonal antibody. Lane 1: CSTF2T transfected lysate(67.76 KDa). Lane 2: Non-transfected lysate.

Applications for CSTF2T Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is useful for Western Blot

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSTF2T

CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously; however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.

Alternate Names

CF-1 64 kDa subunit tau, CF-1 64 kDa subunit tau variant, cleavage stimulation factor 64 kDa subunit tau, Cleavage stimulation factor 64 kDa subunit tau variant, cleavage stimulation factor subunit 2 tau, cleavage stimulation factor subunit 2 tau variant, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant, CSTF 64 kDa subunit tau variant, CstF-64T, DKFZp434C1013, KIAA0689CSTF 64 kDa subunit tau, tauCstF-64

Gene Symbol

CSTF2T

Additional CSTF2T Products

Product Documents for CSTF2T Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CSTF2T Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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