CTDSP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-55471

Novus Biologicals, part of Bio-Techne
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NBP1-55471
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CTDSP2 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to CTDSP2(CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2) Antibody(against the N terminal of CTDSP2. Peptide sequence MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHV. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for CTDSP2 Antibody

Western Blot: CTDSP2 Antibody [NBP1-55471]

Western Blot: CTDSP2 Antibody [NBP1-55471]

Western Blot: CTDSP2 Antibody [NBP1-55471] - Human kidney lysate, concentration 0.2-1 ug/ml.

Applications for CTDSP2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CTDSP2

CTDSP2 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.CTDSP2 negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. CTDSP2 is recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.CTDSP2 may contribute to the development of sarcomas.

Alternate Names

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, conserved gene amplified in osteosarcoma, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 2, NIF2, Nuclear LIM interactor-interacting factor 2, OS4NLI-interacting factor 2, Protein OS-4, PSR2, SCP2EC 3.1.3.16, Small CTD phosphatase 2, Small C-terminal domain phosphatase 2

Gene Symbol

CTDSP2

UniProt

O14595 (Human)

Additional CTDSP2 Products

Product Documents for CTDSP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CTDSP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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