Cullin-7 Antibody (2G11)

Novus Biologicals, part of Bio-Techne | Catalog # H00009820-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2G11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cullin-7 Antibodies »

Product Specifications

Immunogen

CUL7 (AAH33647, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDCKAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVG

Specificity

CUL7 - cullin 7

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Cullin-7 Antibody (2G11)

Western Blot: Cullin-7 Antibody (2G11) [H00009820-M01]

Western Blot: Cullin-7 Antibody (2G11) [H00009820-M01]

Western Blot: Cullin-7 Antibody (2G11) [H00009820-M01] - Detection against Immunogen (36.63 KDa) .
ELISA: Cullin-7 Antibody (2G11) [H00009820-M01]

ELISA: Cullin-7 Antibody (2G11) [H00009820-M01]

ELISA: Cullin-7 Antibody (2G11) [H00009820-M01] - Detection limit for recombinant GST tagged CUL7 is approximately 0.03ng/ml as a capture antibody.

Applications for Cullin-7 Antibody (2G11)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cullin-7

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 7 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 7 seems to be involved proteosomal degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is part of a SCF like complex consisting of CUL7, RBX1, SKP1, FBXW8 and GLMN isoform 1. Cullin 7 interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone.

Alternate Names

CUL-7, cullin 7, cullin-7, KIAA0076dJ20C7.5

Entrez Gene IDs

9820 (Human)

Gene Symbol

CUL7

UniProt

AAH33647 (Human)

Additional Cullin-7 Products

Product Documents for Cullin-7 Antibody (2G11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cullin-7 Antibody (2G11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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