CWC22 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84864

Novus Biologicals, part of Bio-Techne
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NBP1-84864
NBP1-84864-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CWC22 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSRGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CWC22 Antibody

Immunocytochemistry/ Immunofluorescence: CWC22 Antibody [NBP1-84864]

Immunocytochemistry/ Immunofluorescence: CWC22 Antibody [NBP1-84864]

Immunocytochemistry/Immunofluorescence: CWC22 Antibody [NBP1-84864] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.
Immunohistochemistry-Paraffin: CWC22 Antibody [NBP1-84864]

Immunohistochemistry-Paraffin: CWC22 Antibody [NBP1-84864]

Immunohistochemistry-Paraffin: CWC22 Antibody [NBP1-84864] - Staining of human colon shows strong nuclear positivity in glandular cells.

Applications for CWC22 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CWC22

CWC22, also known as Pre-mRNA-splicing factor CWC22 homolog, consists of a long 908 amino acid isoform that is 105 kDa, and is involved in pre-mRNA splicing, though its exact function within the process is still a focus of research. Current disease research is being conducted on the relation between CWC22 and nevus, cerebral malaria, cerebritis, and malaria. The protein is linked to a RNA metabolic processing and mRNA splicing, through which it interacts with DHX15, PRPF6, EIF4A3, FAM32A, and FRG1.

Alternate Names

CWC22 spliceosome-associated protein homolog (S. cerevisiae), EIF4GL, fSAPbpre-mRNA-splicing factor CWC22 homolog, KIAA1604NCMfunctional spliceosome-associated protein b, Nucampholin homolog

Gene Symbol

CWC22

Additional CWC22 Products

Product Documents for CWC22 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CWC22 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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