CXCL4/PF4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46804

Novus Biologicals, part of Bio-Techne
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NBP2-46804
NBP2-46804-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CXCL4/PF4 Antibodies »

Product Summary for CXCL4/PF4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CXCL4/PF4 Antibody

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804] - Staining of human tonsil shows no positivity in germinal center cells as expected.
Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804] - Staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.
Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804]

Immunohistochemistry-Paraffin: CXCL4/PF4 Antibody [NBP2-46804] - Staining of human prostate shows no positivity in glandular cells as expected.
View 1 more images

Applications for CXCL4/PF4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CXCL4/PF4

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM]

Alternate Names

PF4

Entrez Gene IDs

5197 (Human)

Gene Symbol

PF4

UniProt

P10720 (Human)

Additional CXCL4/PF4 Products

Product Documents for CXCL4/PF4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CXCL4/PF4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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