CXCR6 Antibody (SR1646)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22635

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22635-100ul
NBP3-22635-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1646

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CXCR6 Antibodies »

Product Summary for CXCR6 Antibody (SR1646)

Immunogen

A synthesized peptide derived from human CXCR6 (Uniprot #: O00574)

Specificity

Detects endogenous levels of total CXCR6

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CXCR6 Antibody (SR1646)

Western Blot: CXCR6 Antibody (SR1646) [NBP3-22635] -

Western Blot: CXCR6 Antibody (SR1646) [NBP3-22635] - Western blot analysis using NBP3-22635 in JAR cell lysate.

Applications for CXCR6 Antibody (SR1646)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CXCR6

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Alternate Names

Bonzo, CD186, CXCR6, STRL33

Gene Symbol

CXCR6

Additional CXCR6 Products

Product Documents for CXCR6 Antibody (SR1646)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CXCR6 Antibody (SR1646)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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