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Cyclin D2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14460

Novus Biologicals, part of Bio-Techne
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NBP2-14460

Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Human, Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRGIDL

Reactivity Notes

Use in Rat reported in scientific literature (PMID:33326842) Reactivity reported in scientific literature (PMID: 23227862).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cyclin D2 Antibody

Immunocytochemistry/ Immunofluorescence: Cyclin D2 Antibody [NBP2-14460]

Immunocytochemistry/ Immunofluorescence: Cyclin D2 Antibody [NBP2-14460]

Immunocytochemistry/Immunofluorescence: Cyclin D2 Antibody [NBP2-14460] - Staining of 8226, U266, LP-1, KMS12 and Daudi cells. Image submitted by a verified customer review.
Immunohistochemistry: Cyclin D2 Antibody [NBP2-14460]

Immunohistochemistry: Cyclin D2 Antibody [NBP2-14460]

Immunohistochemistry: Cyclin D2 Antibody [NBP2-14460] - Evaluation of Cyclin D2 expression in RCC samples. Immunohistochemistry staining showed a significant decrease of Cyclin D2 protein expression in 43 paired RCC samples in 40X, 100X, 200X magnification. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0161859), licensed under a CC-BY license.
Immunocytochemistry/ Immunofluorescence: Cyclin D2 Antibody [NBP2-14460]

Immunocytochemistry/ Immunofluorescence: Cyclin D2 Antibody [NBP2-14460]

Immunocytochemistry/Immunofluorescence: Cyclin D2 Antibody [NBP2-14460] - Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for Cyclin D2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0161859)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-14460 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cyclin D2

During the G1 phase of the cell cycle, a cell must "choose" between rest and cell division. A small subfamily of cyclin family molecules, termed cyclin D proteins (D1, D2, D3), promotes commitment to mitosis. They accomplish this by interacting with cyclin-dependent kinases (cdk4 and cdk6) to generate Ser/Thr kinase complexes that remove blocks on DNA synthesis.

Alternate Names

CCND2, Vin1

Gene Symbol

CCND2

Additional Cyclin D2 Products

Product Documents for Cyclin D2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cyclin D2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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