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CYFIP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43685

Novus Biologicals, part of Bio-Techne
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NBP2-43685

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (99%), Mouse (100%), Rhesus Macaque (100%), Xenopus (95%), Zebrafish (96%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human CYFIP2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

148 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CYFIP2 Antibody

CYFIP2 Antibody

Immunohistochemistry-Paraffin: CYFIP2 Antibody [NBP2-43685] -

Immunohistochemistry-Paraffin: CYFIP2 Antibody [NBP2-43685] - CYFIP2 antibody [N2C1], Internal detects CYFIP2 protein at cytoplasm and nucleus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse duodenum.
CYFIP2 stained by CYFIP2 antibody [N2C1], Internal (NBP2-43685) diluted at 1:500.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
CYFIP2 Antibody

Western Blot: CYFIP2 Antibody [NBP2-43685] -

Western Blot: CYFIP2 Antibody [NBP2-43685] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with CYFIP2 antibody [N2C1], Internal (NBP2-43685) diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for CYFIP2 Antibody

Application
Recommended Usage

Western Blot

1:5000-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CYFIP2

CYFIP2, also known as Cytoplasmic FMR1-interacting protein 2, includes a 148 kDa and a 146 kDa isoform, and is involved in the initiation of apoptosis and T-cell adhesion. Disease research is currently being conducted to determine the relationship between CYFIP2 and multiple sclerosis, gout, and asthma. The protein has been linked to the Rac1 Pathway, ErbB1 downstream signaling, regulation of actin cytoskeleton, and the immune system. In these pathways and biological processes, CYFIP2 interacts with ABI1, FXR1, GAS7, FXR2, and ABI3.

Alternate Names

cytoplasmic FMR1 interacting protein 2, cytoplasmic FMR1-interacting protein 2, KIAA1168, p53 inducible protein, PIR121p53-inducible protein 121

Gene Symbol

CYFIP2

Additional CYFIP2 Products

Product Documents for CYFIP2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CYFIP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.