CYP24A1 Antibody (SR2038)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21951

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21951-100ul
NBP3-21951-50ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2038

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CYP24A1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human CYP24A1 (Uniprot #: Q07973)

Specificity

Detects endogenous levels of total CYP24A1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

59 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CYP24A1 Antibody (SR2038)

Western Blot: CYP24A1 Antibody (SR2038) [NBP3-21951] -

Western Blot: CYP24A1 Antibody (SR2038) [NBP3-21951] - Western blot analysis using NBP3-21951 in Human fetal liver lysate.
CYP24A1 Antibody (SR2038)

Western Blot: CYP24A1 Antibody (SR2038) [NBP3-21951] -

Western Blot: CYP24A1 Antibody (SR2038) [NBP3-21951] - Western blot analysis of CYP24A1 expression in Human fetal liver lysate.

Applications for CYP24A1 Antibody (SR2038)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CYP24A1

The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.

Long Name

1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

Alternate Names

24-OHase, CYP24, EC 1.14.15.16

Gene Symbol

CYP24A1

Additional CYP24A1 Products

Product Documents for CYP24A1 Antibody (SR2038)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CYP24A1 Antibody (SR2038)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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