CYRPTIC/CFC1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB600-805

Novus Biologicals, part of Bio-Techne
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NB600-805
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Key Product Details

Species Reactivity

Validated:

Mouse

Predicted:

Human (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Cryptic Antibodies »

Product Specifications

Immunogen

Peptide with sequence HFTGRYCEHDQRRSEC corresponding to internal region according to NP_115934.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CYRPTIC/CFC1 Antibody

Immunohistochemistry-Paraffin: CYRPTIC/CFC1 Antibody [NB600-805]

Immunohistochemistry-Paraffin: CYRPTIC/CFC1 Antibody [NB600-805]

Immunohistochemistry-Paraffin: CYRPTIC/CFC1 Antibody [NB600-805] - Staining of Mouse Embryo Liver. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for CYRPTIC/CFC1 Antibody

Application
Recommended Usage

Immunohistochemistry

1 - 2 ug/ml

Immunohistochemistry-Paraffin

1:10-1:500

Peptide ELISA

Detection limit 1:32000
Application Notes
WB: Preliminary experiments gave an approx. 55 kDa band in human breast, placenta and testis lysates after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 24.6 kDa band according to NP_115934.1. The 55 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Mouse Embryonic liver shows staining of the hepatocyte cell membranes.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cryptic

This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. These proteins play key roles in intercellular signaling pathways during vertebrate embryogenesis. Mutations in this gene can cause autosomal visceral heterotaxy. This protein is involved in left-right asymmetric morphogenesis during organ development.

Alternate Names

CFC-1, CFC1

Entrez Gene IDs

55997 (Human)

Gene Symbol

CFC1

UniProt

NP_115934.1 (Human)

Additional Cryptic Products

Product Documents for CYRPTIC/CFC1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CYRPTIC/CFC1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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